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Symptoms of folate deficiency Some of the symptoms that can be caused by a lack of folate include: General symptoms Fatigue Irritability Headache Dizziness Gastrointestinal symptoms Sore tongue Mouth ulcers Diarrhea Loss of appetite Neurological symptoms Numbness and tingling in the hands and feet Confusion Depression Cognitive impairment Dementia Hematological symptoms Anemia (pale skin, shortness of breath) Testing for vitamin B12 and folate deficiency When to test Since vitamin B12 and folate affect many functions in the body and there are many possible symptoms, blood testing for vitamin B12 and folate is commonly ordered by the physicians at the Adult Down Syndrome Center

In a breastfed infant over the age of one month and with normal G6PD, the developmental and health benefits of breastfeeding should be considered along with the mothers clinical need for nitrofurantoin and any potential adverse effects on the breastfed infant from nitrofurantoin or from the underlying maternal condition

& Kang, R

Clinical observations have noted improvements in liver function and enhanced immune activity in patients undergoing regular treatments

Some individuals may also experience digestive discomfort at higher intake levels